CORDIS · 101019560 · H2020

cfChIP Plasma epigenomics: A new liquid biopsy paradigm

Coordinator: THE HEBREW UNIVERSITY OF JERUSALEM (IL)

Genomic DNA is packaged by histone proteins that carry a multitude of post-translational modifications, which reflect cellular transcriptional states. When cells die, fragmented chromatin retaining histone modifications is released to the circulation. Recently, we pioneered chromatin immunoprecipitation of cell-free nucleosomes carrying active chromatin marks followed by sequencing (cfChIP-seq). Our results show that cfChIP-seq provides multidimensional epigenetic information and that the plasma epigenome contains rich information about the identity and the transcriptional state of the origin…

EU contribution
€3.0M
Total cost
€3.0M
Period
2021-08-01 → 2026-07-31
Framework
Horizon 2020 (2014–2020)
Funding scheme
ERC-ADG
Call
ERC-2020-ADG
Status
SIGNED

About Horizon 2020 (2014–2020)

Horizon 2020 was the EU's flagship research and innovation programme for 2014–2020, with a budget of around €77 billion. It bundled FP7's strands with the EIT and the Competitiveness and Innovation Programme, introduced a stronger societal-challenge orientation, and pushed the funding logic toward closer-to-market innovation. New calls closed in 2020 but funded projects continued through 2024.

EU contribution: €3.0M awarded to the consortium. The project runs over approximately 5 years from 2021-08-01 to 2026-07-31.

Full record on CORDIS — partners, deliverables, publications, news.

Open on cordis.europa.eu → Grant DOI ↗

Frequently asked questions

Who funds this research project?
This project is funded by the European Union through the Horizon 2020 (2014–2020) programme, under the ERC-ADG funding scheme.
What is the EU contribution?
The European Commission contributes €3.0M toward a total project budget of €3.0M.
Which EU programme funds it?
The project is funded under Horizon 2020 (2014–2020), call ERC-2020-ADG.
Who coordinates the project?
The project is coordinated by THE HEBREW UNIVERSITY OF JERUSALEM (IL).
What is the project timeline?
The project runs from 2021-08-01 to 2026-07-31 — approximately 5 years.
Where can I find the full project record?
The complete record — partners, deliverables, publications and news — is published on CORDIS under project ID 101019560.