CORDIS · 101170455 · HORIZON

GLYCOCIRC Sugars maketh the brain: investigating the role of neuronal glycocalyx in shaping the architecture of emerging circuits

Coordinator: VILNIAUS UNIVERSITETAS (LT)

Neuronal glycocalyx has been recently recognized as an active agent that contributes to neuronal synapse formation, neuron excitability as well as neuron-autonomous and microglia-dependent brain network remodelling. In particular, the glycan-terminating sialic acids, which often dominate the ends of the chains of glycoproteins and glycolipids on neuronal surface, are required for appropriate brain development and function. Interestingly, almost a fifth of sialic acid biology genes have human-specific changes and aberrant neuronal sialylation and desialylation are implicated in different neuro…

EU contribution
€2.0M
Total cost
€2.0M
Period
2025-09-01 → 2030-08-31
Framework
Horizon Europe (2021–2027)
Funding scheme
HORIZON-ERC
Call
ERC-2024-COG
Status
SIGNED

About Horizon Europe (2021–2027)

Horizon Europe is the EU's current research and innovation programme, covering 2021 to 2027 with a budget of roughly €95.5 billion. Its three pillars are Excellent Science (frontier research and mobility), Global Challenges and European Industrial Competitiveness (mission-driven collaborative projects in health, climate, digital, security and food) and Innovative Europe (the EIC and EIT). It also funds five EU Missions targeting cancer, climate adaptation, smart cities, oceans and soils.

EU contribution: €2.0M awarded to the consortium. The project runs over approximately 5 years from 2025-09-01 to 2030-08-31.

Full record on CORDIS — partners, deliverables, publications, news.

Open on cordis.europa.eu → Grant DOI ↗

Frequently asked questions

Who funds this research project?
This project is funded by the European Union through the Horizon Europe (2021–2027) programme, under the HORIZON-ERC funding scheme.
What is the EU contribution?
The European Commission contributes €2.0M toward a total project budget of €2.0M.
Which EU programme funds it?
The project is funded under Horizon Europe (2021–2027), call ERC-2024-COG.
Who coordinates the project?
The project is coordinated by VILNIAUS UNIVERSITETAS (LT).
What is the project timeline?
The project runs from 2025-09-01 to 2030-08-31 — approximately 5 years.
Where can I find the full project record?
The complete record — partners, deliverables, publications and news — is published on CORDIS under project ID 101170455.