CORDIS · 101188520 · HORIZON
CoMBi Functional cofactors for targeted modification of biomolecules
Coordinator: VILNIAUS UNIVERSITETAS (LT)
Enzymatic addition of a methyl group (methylation) is the most prevalent natural modification in cells, serving a myriad of regulatory and structural functions. Abnormal methylation of DNA, RNA or histone proteins can lead to severe developmental defects and is associated with numerous human diseases. Selective methylation of biomolecular targets is carried out by dedicated methyltransferase enzymes, which use the cofactor S-adenosyl-L-methionine (AdoMet) as the source of methyl groups. Despite the high specificity and impressive diversity of MTases, the deposited methyl groups are poor repor…
About Horizon Europe (2021–2027)
Horizon Europe is the EU's current research and innovation programme, covering 2021 to 2027 with a budget of roughly €95.5 billion. Its three pillars are Excellent Science (frontier research and mobility), Global Challenges and European Industrial Competitiveness (mission-driven collaborative projects in health, climate, digital, security and food) and Innovative Europe (the EIC and EIT). It also funds five EU Missions targeting cancer, climate adaptation, smart cities, oceans and soils.
0 EU contribution: €150k awarded to the consortium. The project runs over approximately 1.5 years from 2025-04-01 to 2026-09-30.
Full record on CORDIS — partners, deliverables, publications, news.
Open on cordis.europa.eu → Grant DOI ↗More from LT
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Frequently asked questions
- Who funds this research project?
- This project is funded by the European Union through the Horizon Europe (2021–2027) programme, under the HORIZON-ERC-POC funding scheme.
- What is the EU contribution?
- The European Commission contributes €150k.
- Which EU programme funds it?
- The project is funded under Horizon Europe (2021–2027), call ERC-2024-POC.
- Who coordinates the project?
- The project is coordinated by VILNIAUS UNIVERSITETAS (LT).
- What is the project timeline?
- The project runs from 2025-04-01 to 2026-09-30 — approximately 1.5 years.
- Where can I find the full project record?
- The complete record — partners, deliverables, publications and news — is published on CORDIS under project ID 101188520.