CORDIS · 101198168 · HORIZON

GI-DYNAMICS Exploring the dynamics of the gastrointestinal tract using shed cell and spatial transcriptomics

Coordinator: WEIZMANN INSTITUTE OF SCIENCE (IL)

The gastrointestinal (GI) tract undergoes significant changes during post-natal development and in response to various diseases. Single-cell atlases are static and therefore fail to capture the dynamic changes occurring within the GI tract. We have devised a method to transcriptomically profile cells that are naturally shed into the GI tract. Contrary to earlier beliefs, we found that shed cells remain viable and can robustly be measured in fecal samples. Shed cell transcriptomics enables non-invasive tracking of cellular states throughout development and disease progression. Moreover, discre…

EU contribution
€2.5M
Total cost
€0
Period
2025-12-01 → 2030-11-30
Framework
Horizon Europe (2021–2027)
Funding scheme
HORIZON-ERC
Call
ERC-2024-ADG
Status
SIGNED

About Horizon Europe (2021–2027)

Horizon Europe is the EU's current research and innovation programme, covering 2021 to 2027 with a budget of roughly €95.5 billion. Its three pillars are Excellent Science (frontier research and mobility), Global Challenges and European Industrial Competitiveness (mission-driven collaborative projects in health, climate, digital, security and food) and Innovative Europe (the EIC and EIT). It also funds five EU Missions targeting cancer, climate adaptation, smart cities, oceans and soils.

0 EU contribution: €2.5M awarded to the consortium. The project runs over approximately 5 years from 2025-12-01 to 2030-11-30.

Full record on CORDIS — partners, deliverables, publications, news.

Open on cordis.europa.eu → Grant DOI ↗

Frequently asked questions

Who funds this research project?
This project is funded by the European Union through the Horizon Europe (2021–2027) programme, under the HORIZON-ERC funding scheme.
What is the EU contribution?
The European Commission contributes €2.5M.
Which EU programme funds it?
The project is funded under Horizon Europe (2021–2027), call ERC-2024-ADG.
Who coordinates the project?
The project is coordinated by WEIZMANN INSTITUTE OF SCIENCE (IL).
What is the project timeline?
The project runs from 2025-12-01 to 2030-11-30 — approximately 5 years.
Where can I find the full project record?
The complete record — partners, deliverables, publications and news — is published on CORDIS under project ID 101198168.