CORDIS · 101220749 · HORIZON

IMMUNAGENOMICS Immunogenomic and ageing determinants of therapy response in brain metastasis

Coordinator: LUXEMBOURG INSTITUTE OF HEALTH (LU)

Cancer represents a critical public health issue, with 2.74 million new cases diagnosed in Europe in 2022. Most cancer-related deaths are attributed to metastatic spread and it is estimated that 20-40% of all cancer patients will develop metastases to the brain (BrM), facing a dismal prognosis. Novel immunotherapies have shown promising outcomes in BrM patients, although a substantial proportion remain unresponsive. This reflects the heterogeneous nature of the tumor immune microenvironment (TIME) and emphasizes the need for a better understanding of its role driving pro- or anti-tumoral resp…

EU contribution
€1.5M
Total cost
€1.5M
Period
2026-02-01 → 2031-01-31
Framework
Horizon Europe (2021–2027)
Funding scheme
HORIZON-ERC
Call
ERC-2025-STG
Status
SIGNED

About Horizon Europe (2021–2027)

Horizon Europe is the EU's current research and innovation programme, covering 2021 to 2027 with a budget of roughly €95.5 billion. Its three pillars are Excellent Science (frontier research and mobility), Global Challenges and European Industrial Competitiveness (mission-driven collaborative projects in health, climate, digital, security and food) and Innovative Europe (the EIC and EIT). It also funds five EU Missions targeting cancer, climate adaptation, smart cities, oceans and soils.

EU contribution: €1.5M awarded to the consortium. The project runs over approximately 5 years from 2026-02-01 to 2031-01-31.

Full record on CORDIS — partners, deliverables, publications, news.

Open on cordis.europa.eu → Grant DOI ↗

Frequently asked questions

Who funds this research project?
This project is funded by the European Union through the Horizon Europe (2021–2027) programme, under the HORIZON-ERC funding scheme.
What is the EU contribution?
The European Commission contributes €1.5M toward a total project budget of €1.5M.
Which EU programme funds it?
The project is funded under Horizon Europe (2021–2027), call ERC-2025-STG.
Who coordinates the project?
The project is coordinated by LUXEMBOURG INSTITUTE OF HEALTH (LU).
What is the project timeline?
The project runs from 2026-02-01 to 2031-01-31 — approximately 5 years.
Where can I find the full project record?
The complete record — partners, deliverables, publications and news — is published on CORDIS under project ID 101220749.