CORDIS · 101224668 · HORIZON

CenAGE CenAGE, a 'Centromeric' view on AGEing: unveiling centromere instability in ageing

Coordinator: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR)

Ageing is the primary risk factor for chronic diseases. Amongst the ageing hallmarks, genomic instability has emerged as a unifying cause of ageing, since it drives most of the other hallmarks, namely senescence and chronic inflammation. These hallmarks are all typically portrayed by the aged immune system, with compelling evidence pointing to genomic instability in immune cells as a driver of organismal ageing. Intriguingly, while the role of telomeres, mutations, transposons, etc, in age-related genomic instability has been widely investigated, the centromeres have remained largely overlook…

EU contribution
€10.0M
Total cost
€10.0M
Period
2026-04-01 → 2032-03-31
Framework
Horizon Europe (2021–2027)
Funding scheme
HORIZON-ERC-SYG
Call
ERC-2025-SyG
Status
SIGNED

About Horizon Europe (2021–2027)

Horizon Europe is the EU's current research and innovation programme, covering 2021 to 2027 with a budget of roughly €95.5 billion. Its three pillars are Excellent Science (frontier research and mobility), Global Challenges and European Industrial Competitiveness (mission-driven collaborative projects in health, climate, digital, security and food) and Innovative Europe (the EIC and EIT). It also funds five EU Missions targeting cancer, climate adaptation, smart cities, oceans and soils.

EU contribution: €10.0M awarded to the consortium. The project runs over approximately 6 years from 2026-04-01 to 2032-03-31.

Full record on CORDIS — partners, deliverables, publications, news.

Open on cordis.europa.eu → Grant DOI ↗

Frequently asked questions

Who funds this research project?
This project is funded by the European Union through the Horizon Europe (2021–2027) programme, under the HORIZON-ERC-SYG funding scheme.
What is the EU contribution?
The European Commission contributes €10.0M toward a total project budget of €10.0M.
Which EU programme funds it?
The project is funded under Horizon Europe (2021–2027), call ERC-2025-SyG.
Who coordinates the project?
The project is coordinated by INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR).
What is the project timeline?
The project runs from 2026-04-01 to 2032-03-31 — approximately 6 years.
Where can I find the full project record?
The complete record — partners, deliverables, publications and news — is published on CORDIS under project ID 101224668.