CORDIS · 101252959 · HORIZON
LIGAND-AI Protein-ligand data generation at scale to support computational hit finding and optimization
Coordinator: STRUCTURAL GENOMICS CONSORTIUM LBG (UK)
The ability to discover and optimize small-molecule ligands by using innovative physics-based, machine learning (ML) and artificial intelligence (AI) approaches would transform and democratize the discovery of new small molecule drugs and related research tools (chemical probes), with important implications for the development of new medicines for rare and pediatric diseases, cancer, and women’s health. The development of these methods is being held back by the lack of high-quality protein-ligand data in the public domain. To fill this gap, we have assembled a multi-sector public-private part…
About Horizon Europe (2021–2027)
Horizon Europe is the EU's current research and innovation programme, covering 2021 to 2027 with a budget of roughly €95.5 billion. Its three pillars are Excellent Science (frontier research and mobility), Global Challenges and European Industrial Competitiveness (mission-driven collaborative projects in health, climate, digital, security and food) and Innovative Europe (the EIC and EIT). It also funds five EU Missions targeting cancer, climate adaptation, smart cities, oceans and soils.
EU contribution: €29.9M awarded to the consortium. The project runs over approximately 5 years from 2025-11-01 to 2030-10-31.
Full record on CORDIS — partners, deliverables, publications, news.
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Other HORIZON projects
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- PARC — Partnership for the Assessment of Risks from Chemicals101057014 · FR · €200.0M
- EIT RM BP23-25 — EIT RawMatrials Business Plan 2023-2025101113034 · DE · €155.5M
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Frequently asked questions
- Who funds this research project?
- This project is funded by the European Union through the Horizon Europe (2021–2027) programme, under the HORIZON-JU-RIA funding scheme.
- What is the EU contribution?
- The European Commission contributes €29.9M.
- Which EU programme funds it?
- The project is funded under Horizon Europe (2021–2027), call HORIZON-JU-IHI-2025-09-single-stage.
- Who coordinates the project?
- The project is coordinated by STRUCTURAL GENOMICS CONSORTIUM LBG (UK).
- What is the project timeline?
- The project runs from 2025-11-01 to 2030-10-31 — approximately 5 years.
- Where can I find the full project record?
- The complete record — partners, deliverables, publications and news — is published on CORDIS under project ID 101252959.