CORDIS · 248289 · FP7

BCELLSMICETOMEN Translational study on the antigen presenting properties of human vs mouse B cell subpopulations

Coordinator: THE STEPHAN ANGELOFF INSTITUTE OF MICROBIOLOGY, BULGARIAN ACADEMY OF SCIENCES (BG)

Our recent results on antitumor effects of carbohydrate mimotope peptides (CMP) suggest a possible role of carbohydrate reactive B cell subpopulations as cellular adjuvants. As an abundant alternative of dendritic cells, CD40-activated B cells can efficiently present specific antigens being expandable for several weeks. Some B cells can be sufficiently detrimental to warrant anti-B cell therapy in cancer. Other (mouse) B cell subsets (e.g. B1 and marginal zone (MZ) B cells) seem as effective as mature DC, including skewing the T cell to the desirable Th1 responses. Thus, B subpopulations dese…

EU contribution
€75k
Total cost
€75k
Period
2010-04-15 → 2013-04-14
Framework
Seventh Framework Programme (2007–2013)
Funding scheme
MC-IRG
Status
CLOSED

About Seventh Framework Programme (2007–2013)

The Seventh Framework Programme (FP7) ran from 2007 to 2013 and was the EU's main research-funding instrument of that period. It mobilised roughly €50 billion across cooperation projects, ERC frontier grants, Marie Curie fellowships, capacity-building actions and Euratom research. FP7 closed to new calls in 2013 but its projects continued for years after under their original grant agreements.

EU contribution: €75k awarded to the consortium. The project runs over approximately 3 years from 2010-04-15 to 2013-04-14.

Full record on CORDIS — partners, deliverables, publications, news.

Open on cordis.europa.eu →

Frequently asked questions

Who funds this research project?
This project is funded by the European Union through the Seventh Framework Programme (2007–2013) programme, under the MC-IRG funding scheme.
What is the EU contribution?
The European Commission contributes €75k toward a total project budget of €75k.
Which EU programme funds it?
The project is funded under Seventh Framework Programme (2007–2013).
Who coordinates the project?
The project is coordinated by THE STEPHAN ANGELOFF INSTITUTE OF MICROBIOLOGY, BULGARIAN ACADEMY OF SCIENCES (BG).
What is the project timeline?
The project runs from 2010-04-15 to 2013-04-14 — approximately 3 years.
Where can I find the full project record?
The complete record — partners, deliverables, publications and news — is published on CORDIS under project ID 248289.