CORDIS · 277899 · FP7

4DCELLFATE Developing a global understanding of the PRC and NuRD complexes in stem cell differentiation, in health and disease

Coordinator: FUNDACIO CENTRE DE REGULACIO GENOMICA (ES)

Embryonic stem (ES) cells have the potential to differentiate into any type of cell as well as to renew indefinitely in culture. They hold great potential for the development of personalized medicines. However, the molecular mechanisms underpinning cell fate decisions by individual cells are poorly understood. There is compelling evidence that two large multi-protein machines, the Nucleosome Remodelling and Deacetylation (NuRD) complex and the Polycomb Repressive Complexes (PRCs), modulate chromatin structure to control stem cell renewal, lineage commitment and differentiation. Moreover, they…

EU contribution
€12.0M
Total cost
Period
2011-12-01 → 2016-11-30
Framework
Seventh Framework Programme (2007–2013)
Funding scheme
CP-IP
Status
CLOSED

About Seventh Framework Programme (2007–2013)

The Seventh Framework Programme (FP7) ran from 2007 to 2013 and was the EU's main research-funding instrument of that period. It mobilised roughly €50 billion across cooperation projects, ERC frontier grants, Marie Curie fellowships, capacity-building actions and Euratom research. FP7 closed to new calls in 2013 but its projects continued for years after under their original grant agreements.

EU contribution: €12.0M awarded to the consortium. The project runs over approximately 5 years from 2011-12-01 to 2016-11-30.

Full record on CORDIS — partners, deliverables, publications, news.

Open on cordis.europa.eu →

Frequently asked questions

Who funds this research project?
This project is funded by the European Union through the Seventh Framework Programme (2007–2013) programme, under the CP-IP funding scheme.
What is the EU contribution?
The European Commission contributes €12.0M.
Which EU programme funds it?
The project is funded under Seventh Framework Programme (2007–2013).
Who coordinates the project?
The project is coordinated by FUNDACIO CENTRE DE REGULACIO GENOMICA (ES).
What is the project timeline?
The project runs from 2011-12-01 to 2016-11-30 — approximately 5 years.
Where can I find the full project record?
The complete record — partners, deliverables, publications and news — is published on CORDIS under project ID 277899.