CORDIS · 883552 · H2020
ONCODESTROYER Targeting cancer vulnerabilities in acute leukemia
Coordinator: THE HEBREW UNIVERSITY OF JERUSALEM (IL)
Background and rationale: Adult acute leukemias pose a great challenge to cancer therapy, with only few advances made in 50 years. As these malignancies are commonly associated with multiple epigenetic aberrations, epigenetic factors represent attractive leukemia drug targets. Nevertheless, most epigenetic-targeting drugs have displayed limited clinical benefit and key leukemia drivers like MYC, ERG and MYB remained mostly undruggable. We have developed a new class of small molecule kinase inhibitors, termed “oncodestroyers” (ODs), single molecules combining supreme p53 activation with select…
About Horizon 2020 (2014–2020)
Horizon 2020 was the EU's flagship research and innovation programme for 2014–2020, with a budget of around €77 billion. It bundled FP7's strands with the EIT and the Competitiveness and Innovation Programme, introduced a stronger societal-challenge orientation, and pushed the funding logic toward closer-to-market innovation. New calls closed in 2020 but funded projects continued through 2024.
EU contribution: €3.2M awarded to the consortium. The project runs over approximately 6 years from 2020-10-01 to 2026-09-30.
Full record on CORDIS — partners, deliverables, publications, news.
Open on cordis.europa.eu → Grant DOI ↗More from IL
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Frequently asked questions
- Who funds this research project?
- This project is funded by the European Union through the Horizon 2020 (2014–2020) programme, under the ERC-ADG funding scheme.
- What is the EU contribution?
- The European Commission contributes €3.2M toward a total project budget of €3.2M.
- Which EU programme funds it?
- The project is funded under Horizon 2020 (2014–2020), call ERC-2019-ADG.
- Who coordinates the project?
- The project is coordinated by THE HEBREW UNIVERSITY OF JERUSALEM (IL).
- What is the project timeline?
- The project runs from 2020-10-01 to 2026-09-30 — approximately 6 years.
- Where can I find the full project record?
- The complete record — partners, deliverables, publications and news — is published on CORDIS under project ID 883552.