CORDIS · 897958 · H2020

SinGly Glycobiology of synaptic pruning in a developing brain

Coordinator: VILNIAUS UNIVERSITETAS (LT)

Effective neuron-microglial communication is a prerequisite to achieve the final connectome. It is mediated by both the formation of new synapses and selective removal of unnecessary connections through synaptic pruning. Recent evidences suggest that superfluous connections are eliminated by microglia. Almost 70% of the connections are lost in a primate cortex within six months of life. But what drives this selective elimination of so many synapses is a million-euro question. Identifying neuronal signals that differentiate weak synapses from the strong ones is an emerging frontier in cellular…

EU contribution
€146k
Total cost
€146k
Period
2020-11-01 → 2022-10-31
Framework
Horizon 2020 (2014–2020)
Funding scheme
MSCA-IF
Call
H2020-MSCA-IF-2019
Status
TERMINATED

About Horizon 2020 (2014–2020)

Horizon 2020 was the EU's flagship research and innovation programme for 2014–2020, with a budget of around €77 billion. It bundled FP7's strands with the EIT and the Competitiveness and Innovation Programme, introduced a stronger societal-challenge orientation, and pushed the funding logic toward closer-to-market innovation. New calls closed in 2020 but funded projects continued through 2024.

EU contribution: €146k awarded to the consortium. The project runs over approximately 2 years from 2020-11-01 to 2022-10-31.

Full record on CORDIS — partners, deliverables, publications, news.

Open on cordis.europa.eu → Grant DOI ↗

Frequently asked questions

Who funds this research project?
This project is funded by the European Union through the Horizon 2020 (2014–2020) programme, under the MSCA-IF funding scheme.
What is the EU contribution?
The European Commission contributes €146k toward a total project budget of €146k.
Which EU programme funds it?
The project is funded under Horizon 2020 (2014–2020), call H2020-MSCA-IF-2019.
Who coordinates the project?
The project is coordinated by VILNIAUS UNIVERSITETAS (LT).
What is the project timeline?
The project runs from 2020-11-01 to 2022-10-31 — approximately 2 years.
Where can I find the full project record?
The complete record — partners, deliverables, publications and news — is published on CORDIS under project ID 897958.