CORDIS · 101224119 · HORIZON

snoOPERA Beyond Modification: Defining Hidden Roles of snoRNPs in Ribosome Assembly

Coordinator: UNIVERSITAET GRAZ (AT)

The assembly of new ribosomes is a conserved and tightly regulated process required for the growth of all living beings. Successful ribosome production requires the coordinated action of hundreds of cellular factors, including small nucleolar ribonucleoprotein particles (snoRNPs). Human snoRNP defects or alterations in snoRNP expression are linked to bone marrow disorders, neurodegeneration, and cancer. We recently discovered that a specialized class of snoRNPs play central yet underappreciated roles in orchestrating the earliest events of ribosome assembly, beyond their well-known function o…

EU contribution
€10.0M
Total cost
€10.0M
Period
2026-04-01 → 2032-03-31
Framework
Horizon Europe (2021–2027)
Funding scheme
HORIZON-ERC-SYG
Call
ERC-2025-SyG
Status
SIGNED

About Horizon Europe (2021–2027)

Horizon Europe is the EU's current research and innovation programme, covering 2021 to 2027 with a budget of roughly €95.5 billion. Its three pillars are Excellent Science (frontier research and mobility), Global Challenges and European Industrial Competitiveness (mission-driven collaborative projects in health, climate, digital, security and food) and Innovative Europe (the EIC and EIT). It also funds five EU Missions targeting cancer, climate adaptation, smart cities, oceans and soils.

EU contribution: €10.0M awarded to the consortium. The project runs over approximately 6 years from 2026-04-01 to 2032-03-31.

Full record on CORDIS — partners, deliverables, publications, news.

Open on cordis.europa.eu → Grant DOI ↗

Frequently asked questions

Who funds this research project?
This project is funded by the European Union through the Horizon Europe (2021–2027) programme, under the HORIZON-ERC-SYG funding scheme.
What is the EU contribution?
The European Commission contributes €10.0M toward a total project budget of €10.0M.
Which EU programme funds it?
The project is funded under Horizon Europe (2021–2027), call ERC-2025-SyG.
Who coordinates the project?
The project is coordinated by UNIVERSITAET GRAZ (AT).
What is the project timeline?
The project runs from 2026-04-01 to 2032-03-31 — approximately 6 years.
Where can I find the full project record?
The complete record — partners, deliverables, publications and news — is published on CORDIS under project ID 101224119.