CORDIS · 101224291 · HORIZON

CARAMEL Covalent Chaotropic Membrane Transport for Biotherapeutic Delivery (CARAMEL)

Coordinator: UNIVERSIDAD DE SANTIAGO DE COMPOSTELA (ES)

Finding new synthetic compounds that facilitate membrane transport of impermeable bioactive molecules constitutes one of the grand scientific challenges in chemistry, biology, and medicine. Until today, the design principles of artificial transporters have been mainly restricted to membrane-targeting molecules with segregated hydrophilic and hydrophobic domains. We propose a disruptive strategy that uses boron clusters as membrane carriers that abandon the classical amphiphilic topology and exploit the (super)chaotropicity of boron cluster anions. Chaotropicity, historically associated with t…

EU contribution
€9.9M
Total cost
€9.9M
Period
2026-04-01 → 2032-03-31
Framework
Horizon Europe (2021–2027)
Funding scheme
HORIZON-ERC-SYG
Call
ERC-2025-SyG
Status
SIGNED

About Horizon Europe (2021–2027)

Horizon Europe is the EU's current research and innovation programme, covering 2021 to 2027 with a budget of roughly €95.5 billion. Its three pillars are Excellent Science (frontier research and mobility), Global Challenges and European Industrial Competitiveness (mission-driven collaborative projects in health, climate, digital, security and food) and Innovative Europe (the EIC and EIT). It also funds five EU Missions targeting cancer, climate adaptation, smart cities, oceans and soils.

EU contribution: €9.9M awarded to the consortium. The project runs over approximately 6 years from 2026-04-01 to 2032-03-31.

Full record on CORDIS — partners, deliverables, publications, news.

Open on cordis.europa.eu → Grant DOI ↗

Frequently asked questions

Who funds this research project?
This project is funded by the European Union through the Horizon Europe (2021–2027) programme, under the HORIZON-ERC-SYG funding scheme.
What is the EU contribution?
The European Commission contributes €9.9M toward a total project budget of €9.9M.
Which EU programme funds it?
The project is funded under Horizon Europe (2021–2027), call ERC-2025-SyG.
Who coordinates the project?
The project is coordinated by UNIVERSIDAD DE SANTIAGO DE COMPOSTELA (ES).
What is the project timeline?
The project runs from 2026-04-01 to 2032-03-31 — approximately 6 years.
Where can I find the full project record?
The complete record — partners, deliverables, publications and news — is published on CORDIS under project ID 101224291.