CORDIS · 853800 · H2020

TRIC-TB Boosting Ethionamide efficacy and lowering the dose with a small molecule transcriptional modulators, to overcoming MDR-TB infections and define a new place for Ethionamide in 1st-line TB treatments.

Coordinator: BIOVERSYS AG (CH)

Tuberculosis (TB) is the world’s leading infectious disease. It killed 1.7 million people in 2016 and 10.4 million people developed active TB in the same year. In 2016, 480’000 of TB cases were multidrug-resistant (MDR-TB) and 9% percent of those cases are extensively drug-resistant (XDR), with mortality rates as high as 70%. Ethionamide (ETH) is a vital part of the WHO essential medicines list of 2nd-line TB therapy for MDR-TB, however, ETH suffers from significant levels of resistance and side effects at current dosing levels. BVL-GSK038 and BVL-GSK098 are proprietary to BioVersys/GlaxoSmit…

EU contribution
€6.9M
Total cost
€8.4M
Period
2019-05-01 → 2024-02-29
Framework
Horizon 2020 (2014–2020)
Funding scheme
RIA
Call
H2020-JTI-IMI2-2018-16-single-stage
Status
CLOSED

About Horizon 2020 (2014–2020)

Horizon 2020 was the EU's flagship research and innovation programme for 2014–2020, with a budget of around €77 billion. It bundled FP7's strands with the EIT and the Competitiveness and Innovation Programme, introduced a stronger societal-challenge orientation, and pushed the funding logic toward closer-to-market innovation. New calls closed in 2020 but funded projects continued through 2024.

Co-funding: the European Union contributes €6.9M toward a total project budget of €8.4M — a funding rate of 83%, with the remainder covered by the consortium partners. The project runs over approximately 4.8 years from 2019-05-01 to 2024-02-29.

Full record on CORDIS — partners, deliverables, publications, news.

Open on cordis.europa.eu → Grant DOI ↗

Frequently asked questions

Who funds this research project?
This project is funded by the European Union through the Horizon 2020 (2014–2020) programme, under the RIA funding scheme.
What is the EU contribution?
The European Commission contributes €6.9M toward a total project budget of €8.4M.
Which EU programme funds it?
The project is funded under Horizon 2020 (2014–2020), call H2020-JTI-IMI2-2018-16-single-stage.
Who coordinates the project?
The project is coordinated by BIOVERSYS AG (CH).
What is the project timeline?
The project runs from 2019-05-01 to 2024-02-29 — approximately 4.8 years.
Where can I find the full project record?
The complete record — partners, deliverables, publications and news — is published on CORDIS under project ID 853800.